Katherine Heigl

While Katherine Heigl entered the Hollywood scene at an early age, her rapid rise to prominence was anything but spectacular. Her big break came when she was cast as Isabel Stevens on “Grey’s Anatomy,” a medical drama series created by Shonda Rhimes.

In 2010, when accepting the ShoWest Award for Female Star of the Year, the “Killers” actress experienced an embarrassing wardrobe mishap. A strap on her red Donna Karan dress broke while she was on stage, and she was struggling to continue her acceptance speech. However, Billy Bush quickly came to her rescue so she could finish her speech.